Tuesday, May 5, 2009

Tay Sachs Disease =(

There is a terrible disease that is on Earth, and it is known as Tay Sachs disease. This disease was discovered by Warren Tay, a British opthamologist, who described the red spot on the retina in 1881. As you may know, the symptoms for Tay Sachs is a "cherry -red" spot in the retina( or the back of the eye). Infants with Tay Sachs disease can become blind, deaf and unable to swallow because of nerve cells becoming distended with gangliosides, a relentless deterioration of mental and physical abilities occur. Muscles begin to atrophy and paralysis set in. Finally, death occurs at the age of 4. Also, it's rare if a juvenile gets it(2-10 years) and develop speech and swallowing difficulties and spasticity. Then, they usually die between 5-15 years old. Unfortunately, there is no cure for this fatal disease. Infants mortality rate is 4, juveniles 5-15 and adults is 20s to early 30s. 1 out of every 250 people will develope Tay Sachs disease and 16 in the U.S. will develop it too. Mostly, it's more common in Jewish people because of their origin. 95% of Ashkenazi Jews are carriers. Tay Sachs occur when the absence of a vital enzyme called hexosaminidase A. It's the absence of Hex-A(hexosaminidase A), a fatty substance or lipid called GM2 ganglioside accumulates abnormally in cells, especially in the nerve cells of a brain. This ongoing accumulation results in ongoing damage to the cells. Worst of all, absolutely nothing can treat it nor cure it. In my opinion, more people internationally should become aware about Tay Sachs disease. Also, more fundraisers for Tay Sachs research should take place to try to find a cure for this cure less disease. This disease takes too many lives, and we(the people of the United States and people of other countries around the world)need to put our differences aside and find a cure.

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